Nolvadex (Tamoxifen) is one of the oldest and most popular selective estrogen receptor modulators (SERM’s) in the world. Tamoxifen Citrate was developed in 1961 by Imperial Chemical Industries (ICI) under the trade name Nolvadex. Later, AstraZeneca purchased ICI. Tamoxifen can be used to treat a large amount of dysfunctions, that’s why it was included in the World Health Organization’s list of essential medications. Nolvadex is also widely used by androgenic anabolic steroid users. The drug was created to treat hormone-responsive breast cancer, then it turned out that it also can be used to prevent breast cancer. Nolvadex also can be used to treat women’s infertility, however studies have shown less effective results than from Clomid (Clomiphene).

Clomid or Clomiphene is a selective estrogen receptor modulator (SERM), it is very similar to another popular SERM, Nolvadex (Tamoxifen). Mostly Clomid is used for ovulation induction for infertile patients. Clomid has been used since the 1960’s, initially it was used by women with infrequent menstruation. In the middle of the 1970’s the drug became very popular as a strong fertility aid and it still continues being used with that goal today. The research has shown a great result among infertile women. Clomid is also one of the most used selective estrogen receptor modulators by androgenic anabolic steroid users. The drug is not an androgenic anabolic steroid but can be used to reduce estrogenic side effects that can be caused by using steroids. There are better drugs on the market to reduce estrogenic side effects such as Anastrozole, Proviron, etc.